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Kombiglyze XR 2.5/1000 mg Tablets (56 tablets) is a combination medication used to manage type 2 diabetes. It contains two active ingredients: Saxagliptin and Metformin, which work together to help control blood sugar levels. Composition: Active Ingredients: Saxagliptin: 2.5 mg. Metformin Hydrochloride: 1000 mg. Indications: Kombiglyze XR is primarily prescribed for: Type 2 Diabetes: It is used as part of a treatment regimen to help improve blood glucose control in adults with type 2 diabetes, particularly when diet and exercise alone do not achieve sufficient control. As an Adjunct to Diet and Exercise: Kombiglyze XR is typically used alongside a healthy diet and physical activity plan to manage blood glucose levels in people with type 2 diabetes. Mechanism of Action: The two active ingredients in Kombiglyze XR work in different ways to help control blood sugar: Saxagliptin: This is a DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor). It works by increasing the levels of incretin hormones, which in turn increases insulin secretion from the pancreas and decreases the amount of glucose produced by the liver, particularly after meals. Metformin: This is a biguanide that works by: Reducing hepatic glucose production (production of glucose in the liver). Increasing insulin sensitivity in muscle cells, which helps the body use glucose more effectively. Reducing glucose absorption from the intestines, which helps lower post-meal blood sugar levels.
Direction of Use:
Kombiglyze XR 2.5/1000 mg Tablets (56 tablets) is a combination medication used to manage type 2 diabetes. It contains two active ingredients: Saxagliptin and Metformin, which work together to help control blood sugar levels. Composition: Active Ingredients: Saxagliptin: 2.5 mg. Metformin Hydrochloride: 1000 mg. Indications: Kombiglyze XR is primarily prescribed for: Type 2 Diabetes: It is used as part of a treatment regimen to help improve blood glucose control in adults with type 2 diabetes, particularly when diet and exercise alone do not achieve sufficient control. As an Adjunct to Diet and Exercise: Kombiglyze XR is typically used alongside a healthy diet and physical activity plan to manage blood glucose levels in people with type 2 diabetes. Mechanism of Action: The two active ingredients in Kombiglyze XR work in different ways to help control blood sugar: Saxagliptin: This is a DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor). It works by increasing the levels of incretin hormones, which in turn increases insulin secretion from the pancreas and decreases the amount of glucose produced by the liver, particularly after meals. Metformin: This is a biguanide that works by: Reducing hepatic glucose production (production of glucose in the liver). Increasing insulin sensitivity in muscle cells, which helps the body use glucose more effectively. Reducing glucose absorption from the intestines, which helps lower post-meal blood sugar levels.
Side Effects
Common side effects of Kombiglyze XR include: nausea ,vomitting,diarrhea,headache
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